Study Target Validation in Drug Discovery (0123693934)

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Target Validation in Drug Discovery by Brian W. Metcalf, Susan Dillon

This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book.

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	Medical Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development) Publisher: Wiley-InterscienceNumber Of Pages: Publication Date: 2007-06-29Sales Rank: 2586696ISBN / ASIN: 0471743 ...
	Science/Engineering Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development) Publisher: Wiley-InterscienceLanguage: englishISBN: 047174302XPaperback: 320 pagesData: June 29, 2007Format: PDFDescription: Advances that open new avenues in developing aminoglycoside antibiotics During the last twenty years, there have be ...
	Target Discovery and Validation Reviews and Protocols, Vol 1: Emerging Strategies for Targets and Biomarker Discovery (Methods Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Molecular Biology, Vol 361) AHumana Press \| ISBN:1588296563 \| Edition 2006-10-15 \| PDF \| 376 pages \| 4.1 MB \| Rap ...
	Science/Engineering Target Validation in Drug Discovery (2006) Target Validation in Drug DiscoveryPublisher: Academic Press \| English \| ISBN:0123693934 \| 296 pages \| 2006 \| PDF \| 16 MbDescription: This work presents a comprehensive contemporary framework for approaching target validation in drug disco ...
	Study Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2) (ReUp) Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2) Wiley-Interscience (January 23, 2003) \| ISBN-10: 0471370282 \| 832 pages \| PDF \| 37,6 MB "An essential addition to the libraries of any medicin ...
	Science/Engineering In Silico Technologies in Drug Target Identification and Validation Darryl Leon, Scott Markel, "In Silico Technologies in Drug Target Identification and Validation"Publisher: CRC; 1 edition \| 2006-06-13 \| 481 Pages \| ISBN: 1574444786 \| PDF \| 5,8 MBThe pharmaceutical industry relies on numerous well-designed ...

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	Medical Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development) Publisher: Wiley-InterscienceNumber Of Pages: Publication Date: 2007-06-29Sales Rank: 2586696ISBN / ASIN: 0471743 ...
	Science/Engineering Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development) Publisher: Wiley-InterscienceLanguage: englishISBN: 047174302XPaperback: 320 pagesData: June 29, 2007Format: PDFDescription: Advances that open new avenues in developing aminoglycoside antibiotics During the last twenty years, there have be ...
	Target Discovery and Validation Reviews and Protocols, Vol 1: Emerging Strategies for Targets and Biomarker Discovery (Methods Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Molecular Biology, Vol 361) AHumana Press \| ISBN:1588296563 \| Edition 2006-10-15 \| PDF \| 376 pages \| 4.1 MB \| Rap ...
	Science/Engineering Target Validation in Drug Discovery (2006) Target Validation in Drug DiscoveryPublisher: Academic Press \| English \| ISBN:0123693934 \| 296 pages \| 2006 \| PDF \| 16 MbDescription: This work presents a comprehensive contemporary framework for approaching target validation in drug disco ...
	Study Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2) (ReUp) Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2) Wiley-Interscience (January 23, 2003) \| ISBN-10: 0471370282 \| 832 pages \| PDF \| 37,6 MB "An essential addition to the libraries of any medicin ...
	Science/Engineering In Silico Technologies in Drug Target Identification and Validation Darryl Leon, Scott Markel, "In Silico Technologies in Drug Target Identification and Validation"Publisher: CRC; 1 edition \| 2006-06-13 \| 481 Pages \| ISBN: 1574444786 \| PDF \| 5,8 MBThe pharmaceutical industry relies on numerous well-designed ...

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