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Darryl Leon, Scott Markel, "In Silico Technologies in Drug Target Identification and Validation"

The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets. These in silico methods are often predictive, yielding faster and less expensive analyses than traditional in vivo or in vitro procedures.

In Silico Technologies in Drug Target Identification and Validation addresses the challenge of testing a growing number of new potential targets and reviews currently available in silico approaches for identifying and validating these targets. The book emphasizes computational tools, public and commercial databases, mathematical methods, and software for interpreting complex experimental data. The book describes how these tools are used to visualize a target structure, identify binding sites, and predict behavior. World-renowned researchers cover many topics not typically found in most informaticsbooks, including functional annotation, siRNA design, pathways, text mining, ontologies, systems biology, database management, data pipelining, and pharmacogenomics.

Covering issues that range from prescreening target selection to genetic modeling and valuable data integration, In Silico Technologies in Drug Target Identification and Validation is a self-contained and practical guide to the various computational tools that can accelerate the identification and validation stages of drug target discovery and determine the biological functionality of potential targets more effectively.

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	Target Discovery and Validation Reviews and Protocols, Vol 1: Emerging Strategies for Targets and Biomarker Discovery (Methods Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Molecular Biology, Vol 361) AHumana Press \| ISBN:1588296563 \| Edition 2006-10-15 \| PDF \| 376 pages \| 4.1 MB \| Rap ...
	Science/Engineering Target Validation in Drug Discovery (2006) Target Validation in Drug DiscoveryPublisher: Academic Press \| English \| ISBN:0123693934 \| 296 pages \| 2006 \| PDF \| 16 MbDescription: This work presents a comprehensive contemporary framework for approaching target validation in drug disco ...
	Study Target Validation in Drug Discovery Target Validation in Drug Discovery by Brian W. Metcalf, Susan DillonPublisher: Academic Press 2006 \| ISBN: 0123693934 \| 296 Pages \| PDF \| 4.5 MBThis work presents a comprehensive contemporary framework for approaching target validation in ...
	Science/Engineering Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Molecular Biology, Vol 361) Humana Press \| 1588298906 \| Edition - 2007 \| PDF \| 345 pages \| 3.61 MB \| Rapidshare & ...
	Technical Validation of Toxicogenomic Technologies Title: Validation of Toxicogenomic TechnologiesDescription:Validation of Toxicogenomic Technologies: A Workshop SummaryDetails Here:chempharm.blogspot.com/2007/07/validation-of-toxicogenomic.htmlLinks
	Drug Absorption Studies: In Situ, In Vitro and In Silico Models In the last 15 years, a great number of cell- or tissue-based in vitro models have been introduced into the biopharmaceutics arena. These models mimic the different biological barriers that a drug has to overcome to finally reach its target ...

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	Target Discovery and Validation Reviews and Protocols, Vol 1: Emerging Strategies for Targets and Biomarker Discovery (Methods Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Molecular Biology, Vol 361) AHumana Press \| ISBN:1588296563 \| Edition 2006-10-15 \| PDF \| 376 pages \| 4.1 MB \| Rap ...
	Science/Engineering Target Validation in Drug Discovery (2006) Target Validation in Drug DiscoveryPublisher: Academic Press \| English \| ISBN:0123693934 \| 296 pages \| 2006 \| PDF \| 16 MbDescription: This work presents a comprehensive contemporary framework for approaching target validation in drug disco ...
	Study Target Validation in Drug Discovery Target Validation in Drug Discovery by Brian W. Metcalf, Susan DillonPublisher: Academic Press 2006 \| ISBN: 0123693934 \| 296 Pages \| PDF \| 4.5 MBThis work presents a comprehensive contemporary framework for approaching target validation in ...
	Science/Engineering Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in Molecular Biology, Vol 361) Humana Press \| 1588298906 \| Edition - 2007 \| PDF \| 345 pages \| 3.61 MB \| Rapidshare & ...
	Technical Validation of Toxicogenomic Technologies Title: Validation of Toxicogenomic TechnologiesDescription:Validation of Toxicogenomic Technologies: A Workshop SummaryDetails Here:chempharm.blogspot.com/2007/07/validation-of-toxicogenomic.htmlLinks
	Drug Absorption Studies: In Situ, In Vitro and In Silico Models In the last 15 years, a great number of cell- or tissue-based in vitro models have been introduced into the biopharmaceutics arena. These models mimic the different biological barriers that a drug has to overcome to finally reach its target ...

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