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Technical Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design
Posted on 2010-04-14
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More Proteomics and Protein-Protein Interactions: Biology, Chemistry, Bioinformatics, and Drug Design The rapidly evolving field of protein science has now come to realize the ubiquity and importance of protein-protein interactions. It had been known for some time that proteins may interact with each other to form functional complexes, but it was thought to be the property of only a handful of key proteins. However, with the advent of high throughput proteomics to monitor protein-protein interactions at an organism level, we can now safely state that protein-protein interactions are the norm and not the exception. Thus, protein function must be understood in the larger context of the various binding complexes that each protein may form with interacting partners at a given time in the life cycle of a cell. Proteins are now seen as forming sophisticated interaction networks subject to remarkable regulation. The study of these interaction networks and regulatory mechanism, which I would like to term "systems proteomics," is one of the thriving fields of proteomics. My Links To thank me use my links, please!
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