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Science/Engineering Protein-Protein Interactions as New Drug Targets

Posted on 2010-03-15




Name:Science/Engineering Protein-Protein Interactions as New Drug Targets
ASIN/ISBN:3540728422
Language:English
File size:50 Mb
Publisher: Springer
Pages: 512
Publish Date: 2008-08-06
ISBN: 3540728422
File Type: PDF
File Size: 50 MB
   Science/Engineering Protein-Protein Interactions as New Drug Targets

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Protein-Protein Interactions as New Drug Targets

Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions.

This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.

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