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Study Transporters as Drug Carriers: Structure, Function, Substrates (Methods and Principles in Medicinal Chemistry)

Posted on 2010-03-16




Name:Study Transporters as Drug Carriers: Structure, Function, Substrates (Methods and Principles in Medicinal Chemistry)
ASIN/ISBN:3527316612
Language:English
File size:5 Mb
Language: English
Publish Date: 2009-12-14
ISBN: 3527316612
Pages: 449 pages
File Type: PDF
File Size: 5 MB
Other Info: Wiley-VCH
   Study Transporters as Drug Carriers: Structure, Function, Substrates (Methods and Principles in Medicinal Chemistry)



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Gerhard Ecker, Peter Chiba, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers "Transporters as Drug Carriers: Structure, Function, Substrates (Methods and Principles in Medicinal Chemistry)"

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion.

As a result, this key resource lays the foundations for understanding and investigating the molecular mechanisms for multidrug resistance in cancer cells, microbial resistance to antibiotics and pharmacokinetics in general.

For anyone working with antibiotics and cancer chemotherapeutics, as well as being of prime interest to biochemists and biophysicists.

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