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Science/Engineering The Proteasome in Neurodegeneration

Posted on 2010-03-15




Name:Science/Engineering The Proteasome in Neurodegeneration
ASIN/ISBN:0387284990
Language:English
File size:2.56 Mb
ISBN: 0387284990
Publish Date: 2006-02-07
File Type: PDF
Pages: 306pages
File Size: 2.56 MB
Other Info: Springer
   Science/Engineering The Proteasome in Neurodegeneration

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The Proteasome in Neurodegeneration

There is increasing evidence that links together various common neurodegenerative diseases, such as Parkinson’s and Alzheimer’s diseases. Finding common themes in the pathophysiology of such disorders is increasingly important. This text addresses such a common theme—the proteasome. Since the discovery of the proteasome some 20 years ago, significant strides have been made in our understanding of proteasome biology and our understanding of the role the proteasome plays in a wide variety of biochemical events. Taken together, these studies have confirmed an important role for the proteasome in the fields of cell biology, oncology, immunology, gerontology, and neuroscience. The focus of this book is to provide an in depth analysis and provocative discussion of what role normal and aberrant proteasome function plays in regulating various aspects of brain homeostasis.



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