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Science/Engineering Protein Degradation, Volume 2: The Ubiquitin-Proteasome System
Posted on 2010-03-16
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More R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner, "Protein Degradation, Volume 2: The Ubiquitin-Proteasome System" The second volume in a new series dedicated to protein degradation, this book discusses the mechanism and cellular functions of targeted protein breakdown via the ubiquitin pathway. Drawing on the combined knowledge of the world's leading protein degradation experts, this handy reference compiles information on the proteasome-mediated degradation steps of the ubiquitin pathway. In addition to proteasomal function and regulation, it also presents the latest results on novel members of the ubiquitin superfamily and their role in cellular regulation. Further volumes in the series cover the function of ubiquitin-protein ligases, and the roles of the ubiquitin pathway in regulating key cellular processes, as well as its pathophysiological disease states. Required reading for molecular biologists, cell biologists and physiologists with an interest in protein degradation. From the content: Degrons: signals and sites for ubiquitylation The proteasome portal and regulation of proteolysis PAN and the proteasome Ubiquitin domain proteins MEKK1: dual function as a protein kinase and a ubiquitin protein ligase HECT domain ubiquitin protein ligases UCRP: ubiquitin cross-reactive protein SUMOs and their function in the cell Functions of the ubiquitin-proteasome pathway Molecular Chaperones and the ubiquitin/proteasome system Dissecting intracellular proteolysis using small molecule inhibitors and molecular probes Electron microscopy of compartmentalised proteases Molecular dissection of autophagy in yeast Not all books ... appear on the homepage. In order not to miss many of them follow Download Link (Ebooks section) (see top of each page on AH) and visit too :)
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| Protein Degradation Series, 4 Volume Set R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner “Protein Degradation Series, 4 Volume Set" Wiley-VCH | 2008-03-03 | ISBN: 352731878X | 1203 pages | PDF | 14,6 Mb --mirror-- --mirror-- |
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