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Science/Engineering Structural Bioinformatics (Methods of Biochemical Analysis)

Posted on 2010-03-16




Name:Science/Engineering Structural Bioinformatics (Methods of Biochemical Analysis)
ASIN/ISBN:0471202002
Language:English
File size:19.5 Mb
Publisher: Wiley-Liss
ISBN: 0471202002
Publish Date: edition 2003
File Type: PDF
Pages: 649 pages
File Size: 19,5 mb
   Science/Engineering Structural Bioinformatics (Methods of Biochemical Analysis)

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Structural Bioinformatics (Methods of Biochemical Analysis)

The emerging discipline of structural bioinformatics comprises the development of computational technologies for methods of storage, retrieval, and analysis of the three-dimensional structure of biological macromolecules. Edited by Philip Bourne and Helge Weissig, this groundbreaking text provides a thorough understanding of the theories, associated algorithms, resources, and tools used in structural bioinformatics.

Structural Bioinformatics begins with chapters on the fundamentals of protein structure, DNA/RNA structure, carbohydrates, and techniques including X-ray crystallography, NMR, cryo-electron microscopy, and molecular visualization. The next section addresses data representation and databases, followed by information on structure classification of proteins (SCOP) and class, architecture, topology, and homology (CATH) classification. Later chapters cover structure-function assignment, protein interactions, and proteins as drug targets. Structural Bioinformatics also:

* Covers the theory, biology, resources, and practical applications for computational approaches to biomolecular structural studies

* Provides broad-based, concise coverage with a consistent direction

* Offers detailed coverage for practitioners while remaining accessible to the novice...



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