Medical Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and bioavailability (3527605150)

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Author: Han Van De Waterbeemd , Hans Lennernds, Per Artursson, Raimund Mannhold, Hugo Kubinyi , Gerd Folkers
Publisher: Wiley-VCH
ISBN: 3527605150
Pages: 602

The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The efficacy of drug uptake depends on the one hand on the chemical characteristics of the active substance, above all on its solubility and membrane permeability. On the other hand, it is determined by the organism's ability to absorb pharmaceuticals by way of specific transport proteins or to excrete them. Since many pharmacologically active substances are poorly suited for oral intake, a decisive criterion for the efficacy of a medicine is its so-called bioavailability. Written by an international team from academia and the pharmaceutical industry, this book covers all aspects of the oral bioavailability of medicines. The focus is placed on methods for determining the parameters relevant to bioavailability. These range from modern physicochemical techniques via biological studies in vitro and in vivo left up to computer-aided predictions. The authors specifically address possibilities for optimizing bioavailability during the early screening stage for the active substance. Its clear structure and comprehensive coverage make this book equally suitable for researchers and lecturers in industry and teaching. can any body help by uploading this book Thanks in advance

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	Health Absorption and Drug Development: Solubility, Permeability, and Charge State www.AvaxHome.ruBook Description:Avdeef explains how to test, analyse and profile drug candidates at the in vitro stage (outside the body) so that drugs with poor absorption properties can be eliminated early.Book Info:Published in 2003Publi ...
	Medical Drug Bioavailability
	Science/Engineering Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition Shein-Chung Chow, Jen-pei Liu “Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition" Chapman & Hall/CRC \| 2008-10-15 \| ISBN: 1584886684 \| 760 pages \| PDF \| 3,5 MB Taking into account the regulatory and scien ...
	Science/Engineering Chemical Bioavailability in Terrestrial Environments, Volume 32 Ravendra Naidu, «Chemical Bioavailability in Terrestrial Environments, Volume 32»Elsevier Limited \| ISBN: 0444521690 \| 2008 \| PDF \| 828 pages \| 8.8 MB“This book begins with an overview of current thinking on bioavailability, its def ...
	Science/Engineering Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (Repost) Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability Wiley-VCH \| ISBN: 3527601473 \|Year 2003 \| English \| 579pages\| PDF \|size: 8,99MbThe gold standard for industrial research now completely revised in ...
	Study Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability Han van de Waterbeemd, Bernard Testa, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, "Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability" Wiley-VCH \| 2008 \| ISBN: 3527320512 \| 649 pages \| PDF \| 4,4 ...

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	Health Absorption and Drug Development: Solubility, Permeability, and Charge State www.AvaxHome.ruBook Description:Avdeef explains how to test, analyse and profile drug candidates at the in vitro stage (outside the body) so that drugs with poor absorption properties can be eliminated early.Book Info:Published in 2003Publi ...
	Medical Drug Bioavailability
	Science/Engineering Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition Shein-Chung Chow, Jen-pei Liu “Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition" Chapman & Hall/CRC \| 2008-10-15 \| ISBN: 1584886684 \| 760 pages \| PDF \| 3,5 MB Taking into account the regulatory and scien ...
	Science/Engineering Chemical Bioavailability in Terrestrial Environments, Volume 32 Ravendra Naidu, «Chemical Bioavailability in Terrestrial Environments, Volume 32»Elsevier Limited \| ISBN: 0444521690 \| 2008 \| PDF \| 828 pages \| 8.8 MB“This book begins with an overview of current thinking on bioavailability, its def ...
	Science/Engineering Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (Repost) Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability Wiley-VCH \| ISBN: 3527601473 \|Year 2003 \| English \| 579pages\| PDF \|size: 8,99MbThe gold standard for industrial research now completely revised in ...
	Study Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability Han van de Waterbeemd, Bernard Testa, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, "Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability" Wiley-VCH \| 2008 \| ISBN: 3527320512 \| 649 pages \| PDF \| 4,4 ...

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