Science/Engineering Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability (Repost) (3527601473)

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Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability

The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten.

In 21 chapters readers can benefit from the key working knowledge of today's leading pharmaceutical companies, including Pfizer, AstraZeneca, and Roche. Drug developers from industry and academia present all the factors governing drug bioavailability, complete with practical examples and real-life data.

Part I focuses on in vitro and in vivo measurements of physicochemical properties, such as membrane permeability and ionization. Part II discusses solubility and gastrointestinal absorption, while the third part is devoted to metabolism and excretory mechanisms. The much revised and expanded part IV surveys current in silico approaches to predict drug properties needed to estimate the bioavailability of any new drug candidate. The final part shows how poor bioavailability may be improved by various approaches during the development process.

No other publication offers the same level of treatment on this crucial topic in modern drug development.

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	Health Absorption and Drug Development: Solubility, Permeability, and Charge State www.AvaxHome.ruBook Description:Avdeef explains how to test, analyse and profile drug candidates at the in vitro stage (outside the body) so that drugs with poor absorption properties can be eliminated early.Book Info:Published in 2003Publi ...
	Medical Drug Bioavailability
	Science/Engineering Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition Shein-Chung Chow, Jen-pei Liu “Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition" Chapman & Hall/CRC \| 2008-10-15 \| ISBN: 1584886684 \| 760 pages \| PDF \| 3,5 MB Taking into account the regulatory and scien ...
	Science/Engineering Chemical Bioavailability in Terrestrial Environments, Volume 32 Ravendra Naidu, «Chemical Bioavailability in Terrestrial Environments, Volume 32»Elsevier Limited \| ISBN: 0444521690 \| 2008 \| PDF \| 828 pages \| 8.8 MB“This book begins with an overview of current thinking on bioavailability, its def ...
	Study Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability Han van de Waterbeemd, Bernard Testa, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers, "Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability" Wiley-VCH \| 2008 \| ISBN: 3527320512 \| 649 pages \| PDF \| 4,4 ...
	Medical Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and bioavailability Author: Han Van De Waterbeemd , Hans Lennernds, Per Artursson, Raimund Mannhold, Hugo Kubinyi , Gerd FolkersPublisher: Wiley-VCHISBN: 3527605150Pages: 602The peroral application (swallowing) of a medicine means that the body must first reso ...

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