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Science/Engineering Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens

Posted on 2010-03-16




Name:Science/Engineering Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens
ASIN/ISBN:0849315077
Language:English
File size:3.86 Mb
Publish Date: February 26, 2003
ISBN: 0849315077
Pages: 304 pages
File Type: PDF
File Size: 3.86 mb
Other Info: CRC
   Science/Engineering Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens

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Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens

Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides. Much has been published on the principles of QSAR in this area, but not on their application s to toxic chemicals. This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on chemical mutagens and carcinogens. It synthesizes the body of knowledge and recent advances in this rapidly emerging field through the contributions of leading experts from around the world.Quantitative Structure-Activity Relationship (QSAR) Models of Mutagens and Carcinogens focuses on the use of QSAR modeling in predicting and designing compounds for synthesis and testing of cancer drugs. The authors clearly show how QSAR can contribute to the elucidation of mechanisms, to identifying toxic chemicals solely by their chemical structure, and to the design of safer chemicals. The contents include a general introduction to QSAR theory and extensively reviews virtually all existing QSAR models.

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