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Pharmaceutical Inhalation Aerosol Technology Second Edition Revised and Expanded
Posted on 2010-04-14
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More edited by Anthony J. Hickey ISBN: 0824742532 | 2004 | English This thoroughly revised and expanded reference provides authoritative discussions on the physiologic, pharmacologic, metabolic, molecular, cellular, and physicochemical factors influencing the efficacy and utilization of pharmaceutical aerosols and analyzes the latest science and developments in the generation, administration, and characterization of these compounds�showcasing current clinical applications, the efficiency and limitations of major aerosol products, and emerging aerosol therapies impacting the field. Contents I. Factors Governing Aerosol Deposition and Targeting in the Lung 1. Physiology of the Airways 2. Pharmacology of Therapeutic Aerosols 3. Targeting by Deposition 4. Drug Targeting to the Lung: Chemical and Biochemical Considerations 5. Lung Deposition Simulation 6. Practical Aspects of Imaging Techniques Employed to Study Aerosol Disposition and Clearance 7. Pharmacokinetics and Pharmacodynamics of Drugs Delivered to the Lungs II. Methods of Generation, Administration, and Characterization of Aerosols 8. Theoretical Principles and Devices Used to Generate Aerosols for Research 9. The Design and Development of Inhalation of Drug Delivery Systems 10. Aerosol-Filling Equipment for the Preparation of Pressurized-Pack Pharmaceutical Formulations 11. Methods of Aerosol Particle Size Characterization 12. Summary of Common Approaches to Pharmaceutical Aerosol Administration III. Clinical Aspects of Aerosol Administration and Future Perspectives 13. Therapeutic Aerosols: An Overview from a Clinical Perspective 14. Aerosolized Pentamidine for Treatment and Prophylaxis of Pneumocystis carinii Pneumonia in Patients with Acquired Immunodeficiency Syndrome 15. The Application of Aerosolized Antimicrobial Therapies in Lung Infections 16. Gene Delivery to the Lung 17. Recent Advances Related to the Systemic Delivery of Therapeutic Molecules by Inhalation 18. Modulated Drug Therapy with Inhalation Aerosols: Revisited 19. Pulmonary Delivery Technology: Advances of the Last Decade and Potential for the New Millennium Link: http://rapidshare.de/files/34689961/PIAT2.rar
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