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Study Pancreatology: From Bench to Bedside

Posted on 2010-03-16




Name:Study Pancreatology: From Bench to Bedside
ASIN/ISBN:3642001513
Language:English
File size:2 Mb
Publish Date: 2009
ISBN: 3642001513
Pages: 104 pages
File Type: PDF
File Size: 2 MB
Other Info: Springer
   Study Pancreatology: From Bench to Bedside

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Juan Iovanna, Uktam Ismailov, "Pancreatology: From Bench to Bedside"

Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets. Also, very original results show the unexpected role of lipids as mediators during acute pancreatitis. Gene screening strategies allow the detection of the genes responsible for gemcitabine resistance of pancreatic cancer cells. They lead to the selection of several target genes, in order to suppress the resistance of cells to gemcitabine treatment. The mechanism by which tetrahydrocannabinol is anti-tumoral in pancreatic cancer cells is presented and the use of THC as a promising new therapeutic agent is discussed. Genetic data are shown concerning hundreds of families with hereditary chronic pancreatitis and their possible role in the pathogenesis of the disease. Another very original study addresses the prevention and treatment of pancreatic diseases with diet. In clinical research, convincing data about the use of endoscopic sphicterotomy in the management of acute bilary pancreatitis is presented, based on the experience of a left highly specialized in pancreatic diseases.

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