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Novel Therapeutic Concepts for Targeting Glioma offers a comprehensive collection of current information and the upcoming possibilities for designing new therapies for Glioma by an array of experts ranging from Cell Biologists to Oncologists and Neurosurgeons. A variety of topics cover therapeutic strategies based on Cell Signaling, Gene Therapy, Drug Therapy and Surgical methods providing the reader with a unique opportunity to expand and advance his knowledge of the field.

Contents

Preface

Part 1 Surgical Therapy of Glioma

1 Innovative Surgical Management of Glioma

Part 2 EGFR and Glioma Therapy

2 Advances in the Development of EGFR Targeted Therapies for the Treatment of Glioblastoma

3 Future Perspectives of Enhancing the Therapeutic Efficacy of Epidermal Growth Factor Receptor Inhibition in Malignant Gliomas

Part 3 MicroRNAs in Treatment of Glioma

4 MicroRNAand Glial Tumors: Tiny Relation with Great Potential

5 The Role of microRNAs in Gliomas and Their Potential Applications for Diagnosis and Treatment

Part 4 Inhibition of Invasion in Treatment of Glioma

6 Molecular Targets: Inhibition of Tumor Cell Invasion

Part 5 Blood-Brain Barrier in Glioma Therapy

7 Blood-Brain Barrier and Effectiveness of Therapy Against Brain Tumors

Part 6 Gene Therapy of Glioma

8 Glioma-Parvovirus Interactions: Molecular Insights and Therapeutic Potential

9 The Potential and Challenges of siRNA-Based Targeted Therapy for Treatment of Patients with Glioblastoma

10 Hypoxia Responsive Vectors Targeting Astrocytes in Glioma

Part 7 LGI1 in Treatment of Glioma

11 The Tumor Suppressor Function of LGI1

Part 8 Antioxidant Adaptive Response in Glioma

12 Antioxidant Adaptive Response of Malignant Glioma Related to Resistance to Antitumor Treatment

Part 9 TRP Channels in Glioma Therapy

13 Ionic Channels in the Therapy of Malignant Glioma

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