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Study Natural Products: Drug Discovery and Therapeutic Medicine
Posted on 2010-03-15
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More Lixin Zhang / Arnold L. Demain, Natural Products: Drug Discovery and Therapeutic Medicine A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious. Thanks to the original uploader! DOWNLOAD FROM RAPIDSHARE: ID121533 121533 woembk 10 Jun 2007 17:22 Thanks. == == ID:420824 420824 mevale 12 Jun 2007 10:02 thank you outcaast ID:421497 421497
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