Enzymes and Their Inhibitors: Drug Development (0415334020)

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by H. John Smith (Editor), Claire Simons (Editor)

ISBN: 0415334020-year 2005-English

328 pages –pdf- size: 4,2Mb

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibition provides an overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss various types of enzyme inhibitors and the principles involved in developing them into effective drugs. This book describes the problems that can be encountered in translating results from the bench to the market place, and suggests approaches that circumvent these difficulties. This outstanding text for students in pharmacology and medicinal chemistry is also a valuable professional reference.

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