Drug Metabolizing Enzymes Cytochrome P450 And Other Enzymes In Drug Discovery An pdf (0824742931)

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Drug Metabolism Enzymes: Cytochrome p450 and other enzymes in drug discovery and development: Jae S. Lee, R. Scott Obach, Michael B. Fisher

Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. Drug Metabolizing Enzymes systematizes the latest findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.

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