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Medical Physiology - Principles for Clinical Medicine (4th edition)
Medical Physiology: Principles for Clinical Medicine (4th edition) [Repost]
Hypnosis: Medical, Scientific or Occultic? (repost)
Handbook of Antimicrobial Therapy by Medical Letter, Mark Abramowicz, M.D. and Gianna Zuccotti
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Medical Dosage Calculations: A Dimensional Analysis Approach, 10th Edition (Repost)
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Your Medical Mind: How to Decide What Is Right for You (Repost)
For Dummies Series PDF - [ Medical ]
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Analyzing the Large Number of Variables in Biomedical and Satellite Imagery (Repost)
How to Study in Medical School
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Polyphosphazenes for Biomedical Applications by A. K. Andrianov (Repost)
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Medical Antibiotics as Anti-Inflammatory and Immunomodulatory Agents
Posted on 2010-03-15
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Basic research Kazuhiro Tateda et al. Figure 2 Changes of LPS of P. aeruginosa grown in agar with sub-MICs of macrolide antibiotics. Lane 4: azithromycin 4 g/ml. Consequences on the bactericidal activity of phagocytes The possibility that antibiotic-induced stimulation of oxidant production by phagocytes results in increased bactericidal activity has rarely been investigated: for instance, the enhancement of bacterial killing by cefotaxime-treated PMN in vitro was linked to the pro-oxidative effect of this drug 3 . The cephalosporin cefodizime does not modify the phagocyte oxidative burst in vitro, but restores various phagocytic functions in immunocompromised patients ex vivo: in particular, in chronic hemodialysis patients, with a depressed oxidative response, as assessed by hexosemonophosphate shunt activity, cefodizime given for 10 days, significantly increased this phagocytic response compared to cotrimoxazole and placebo treatment 55 . Similarly, 30 patients with severe bacterial infections were treated with cefodizime or ceftriaxone and the effect of cefodizime and ceftriaxone on the phagocytic capacity and generation of reactive oxygen intermediates after phagocytosis by granulocytes was assessed prior to, during, and after therapy. No reports are available on the consequences of prophylactic administration of cefodizime in patients at risk of infections. Book Info: Published in 2005 ISBN 3764359250 Size 1.77MB Alternative Link:
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