Smi InofCydeKiaAntuAg rar (0849337747)

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Inhibitors of Cyclin-dependent Kinases as Anti-tumor Agents (Crc Enzyme Inhibitors) Publisher: CRC

Number Of Pages: 448

Publication Date: 2006-10-25

Sales Rank: 1232962

ISBN / ASIN: 0849337747

EAN: 9780849337741

Binding: Hardcover

Manufacturer: CRC

Studio: CRC

Average Rating: 5

Total Reviews: 1

Book Description: One of the few books to cover all aspects of cyclin-dependent kinases (CDKs), this volume provides an overview of CDKs as molecular and functional entities, their involvement in different disease processes, and their potential for pharmacological modulation. The first two sections discuss the integration of cell cycle control pathways, opportunities for targeting, targets of inhibitors, and the evaluation of CDK inhibitors. The third section examines the design, development, and chemistry of small molecule CDK inhibitors. The final section assesses the current status of CDK inhibitors in clinical trials, the therapeutic deployment challenges of small molecule inhibitors, and the future development of CDK inhibitors as anticancer agents. Buy Book at Lowest Price on Amazon

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