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Science/Engineering Advances in Medicinal Chemistry, Volume 3

Posted on 2010-03-16




Name:Science/Engineering Advances in Medicinal Chemistry, Volume 3
ASIN/ISBN:155938798X
Language:English
File size:10 Mb
Publisher: Jai Pr
Publish Date: 1995-12-01
Pages: 187 Pages
ISBN: 155938798X
File Type: PDF
File Size: 10 MB
   Science/Engineering Advances in Medicinal Chemistry, Volume 3

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Bruce E. Maryanoff, Cynthia A. Maryanoff, "Advances in Medicinal Chemistry, Volume 3"

Hardbound. Volume 3 of Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophrenia. Chapter 2 relates an account on the discovery of novel antithrombotic drugs based on the RGD motif through a rational design approach. Chapter 3 presents themedicinal chemistry and preclinical development surrounding sertraline, a very important serotonin reuptake drug for the treatment of endogenous depression. Finally, Chapter 4 gives a summary of a series of boronic acid-based immunosuppressants that operate via inhibition of dipeptidypeptidase IV..

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