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Science/Engineering The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders

Posted on 2010-03-15




Name:Science/Engineering The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders
ASIN/ISBN:1420053922
Language:English
File size:4 Mb
Pages: 400 pages
Publisher: CRC; 1 edition (November 14, 2008)
Language: English
ISBN: 1420053922
File Type: PDF
File Size: 4 MB
   Science/Engineering The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders



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The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders

Since their discovery, the potential of histamine H3 receptor ligands in various CNS disorders have received much attention. This resourcepresents recent advances with an emphasis on pharmacology. It covers identification and localization of receptors and the development of novel ligands incorporating pre-clinical and clinical studies indicating earliest possible stages of development.The book provides an overview of histamine as a neurotransmitter and discusses receptor pharmacology, signal transduction, selective ligands, and therapeutic potential. Several chapters address disorders involving H3, including Alzheimer’s, ADHD, sleep disorders, epilepsy, obesity, and psychiatric and neurodegenerative disorders.

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