Science/Engineering The Nucleosome (Treatise on the Nucleus) (Treatise on the Nucleus) (1559389400)

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Science/Engineering The Nucleosome (Treatise on the Nucleus) (Treatise on the Nucleus)

Posted on 2010-04-28

Name:	Science/Engineering The Nucleosome (Treatise on the Nucleus) (Treatise on the Nucleus)
ASIN/ISBN:	1559389400
Publisher:	Elsevier Science (1995)
Pages:	Hardcover, 260 pages
File size:	96 Mb

Science/Engineering The Nucleosome (Treatise on the Nucleus) (Treatise on the Nucleus)

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Publisher: Elsevier Science (1995)

Binding: Hardcover, 260 pages

pricer: $104.95

ISBN-10: 1559389400

editorialreviews

This is the first in a series of volumes concerning the properties of the eukaryotic nucleus. Contributions from several of the most active laboratories are brought together to present a focused overview of a selected aspect of nuclear structure and function. Research on the role of nucleosomal structures in transcriptional regulation is making rapid progress. Experimental work on the accessibility of genes to the transcriptional machinery has clearly established that chromatin structure has a role in the repression of genes. However, this repression is highly selective, dependent upon the formation of specific nucleosomes that contain key regulatory elements. More importantly, genetic analysis and biochemical reconstitution have suggested that nucleosomal structures have an essential role in the activation of transcription, and that in certain instances can actually facilitate the inititation process.

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