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This book presents a collection of health risk assessments for known and emerging hazards that span a continuum. These case studies provide much insight into the ongoing evolution of health risk assessments.

Case studies for existing health risks include psychoactive drug usage in delivery truck drivers and using look-back risk assessment for accidental syringe re-use in healthcare settings. Case studies for emerging risks include precautionary actions to safeguard blood supplies; nanoparticle deposition in the lung; and the epistemic issues surrounding genetically modified organism risk assessments.

The final section of the book deals with advancing health risk assessment analyses through a post-genomics lens and provides case studies on personalized genomics, new data analyses and improving in silico models for risk assessment.

Contents

Part 1 Typical health risk assessment case studies for novel risks

1 The Risk of Blood-Borne Viral Infection due to Syringe Re-Use

2 Professional Drivers and Psychoactive Substances Consumption: First Results from Medical Surveillance at the Workplace in Italy

Part 2 Health risk assessment case studies for emerging risks

3 Xenotropic Murine Leukemia Virus-Related Virus as a Case Study: Using a Precautionary Risk Management Approach for Emerging Blood-Borne Pathogens in Canada

4 Ultrafine and Fine Aerosol Deposition in the Nasal Airways of a 9-Month-Old Girl, a 5-Year- Old Boy and a 53-Year-Old Male

5 Safety, Security and Quality: Lessons from GMO Risk Assessments

Part 3 Improving future risk assessment analyses

6 Breast Cancer Prognostication and Risk Prediction in the Post-Genomic Era

7 Physics of Open Systems: A New Approach to Use Genomics Data in Risk Assessment

8 New Models for the In Vitro Study of Liver Toxicity: 3D Culture Systems and the Role of Bioreactors

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