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"The Cell Cycle. Principles of Control" by David O. Morgan

Primers in Biology

The Cell Cycle is an account of the mechanisms that control cell division, beginning with a description of the phases and main events of the cell cycle and the main model organisms in cell-cycle analysis, including Xenopus, Drosophila, and yeasts. Later chapters focus on the molecules and mechanisms of the cell-cycle control system, including the cyclin-dependent kinase family of protein kinases, the cyclins that activate them, and the signaling molecules that regulate them, and discuss cell-cycle control in development and the failure of controls in cancer.

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The book is part of a series of books constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference, without sacrificing the synthesis that is essential for any text that is to be truly instructive. The diagram above illustrates the modular structure and special features of these books. Each chapter is broken down into two-page sections each covering a defined topic and containing all the text, illustrations, definitions and references relevant to that topic. Within each section, the text is divided into subsections under one-sentence headings that reflect the sequence of ideas and the global logic of the chapter.

The modular structure of the text, and the transparency of its organization, make it easy for instructors to choose their own path through the material and for students to revise; or for working scientists using the book as an up-to-date reference to find the topics they want, and as much of the conceptual context of any individual topic as they may need.

All of the definitions and references are collected together at the end of the book, with the section or sections in which they occur indicated in each case. Glossary definitions may sometimes contain helpful elaboration of the definition in the text, and references contain a full list of authors instead of the abbreviated list in the text.

The Author :

David O Morgan graduated in animal physiology from the University of Calgary in 1980 and then did his doctoral and postdoctoral work in endocrinology with Richard A Roth and William J Rutter, and in virology with Harold Varmus at the University of California, San Francisco, where he is now a Professor in the Departments of Physiology and Biochemistry & Biophysics.

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