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Science/Engineering The Cancer Degradome: Proteases and Cancer Biology

Posted on 2010-03-15




Name:Science/Engineering The Cancer Degradome: Proteases and Cancer Biology
ASIN/ISBN:0387690565
Language:English
File size:8 Mb
Publish Date: 2008-09-29
ISBN: 0387690565
Pages: 1000 pages
File Type: PDF
File Size: 8 MB
Other Info: Springer
   Science/Engineering The Cancer Degradome: Proteases and Cancer Biology

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Dylan Edwards, Gunilla Hoyer-Hansen, Francesco Blasi, B.F. Sloane "The Cancer Degradome: Proteases and Cancer Biology"

This book will aim to cover recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; how their activity can be imaged both in vitro and in vivo; the links that have emerged between proteolysis and cell signalling; how the degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to targeting proteolysis for therapy.

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