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Audiobooks & Video Training SUMO Regulation of Cellular Processes {Repost}

Posted on 2010-10-03




Name:Audiobooks & Video Training SUMO Regulation of Cellular Processes {Repost}
ASIN/ISBN:9048126487
Publisher:Springer
Publish Date:edition 2009
Pages:333 pages
File size:10.7 Mb
Publisher: Springer
ISBN: 9048126487
Publish Date: edition 2009
File Type: PDF
Pages: 333 pages
File Size: 10,7 mb
   Audiobooks & Video Training SUMO Regulation of Cellular Processes {Repost}

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SUMO Regulation of Cellular Processes

Over a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utilizes SUMO as the modifier group covalently attached to target substrates. This state-of-the art review on the sumoylation system deals with protein modification as it pertains to regulation of diverse cellular functions. Each chapter has been written by a leading researcher and covers the role of sumoylation in fundamental biochemical activities (transcription, RNA processing, chromatin remodelling, DNA repair, nucleocytoplasmic transport, ion channel regulation, and metabolic pathways).



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