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Science/Engineering Separation Methods in Drug Synthesis and Purification

Posted on 2010-03-15




Name:Science/Engineering Separation Methods in Drug Synthesis and Purification
ASIN/ISBN:0444500073
Language:English
File size:42 Mb
Publish Date: October 1, 2000
ISBN: 0444500073 612 pages
File Type: PDF
File Size: 42 Mb
Other Info: Elsevier Science; 1 edition
   Science/Engineering Separation Methods in Drug Synthesis and Purification

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Separation Methods in Drug Synthesis and Purification

Hardbound. The new technologies in drug research such as combinatorial chemistry, high throughput screening, and robotics have made it possible to synthesise millions of molecules for thousands of screens. This volume presents the theory and applications of a wide range of separation methods used in the early stages of drug synthesis, purification and characterisation. The topics covered are high performance liquid chromatography, capillary electrophoresis, capillary electro-chromatography, enantioseparations, preparative chromatography, and thin-layer chromatography. The separation methods used for the determination of physical-chemical properties together with the quantitative structure–retention relationship studies are also reviewed. The academic contributors provide a detailed description of the basic principles while the industrial contributors give real life examples of their application.

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