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Science/Engineering Quadruplex Nucleic Acids

Posted on 2010-03-15




Name:Science/Engineering Quadruplex Nucleic Acids
ASIN/ISBN:0854043748
Language:English
File size:115.7 Mb
Publish Date: 2006-11-09
ISBN: 0854043748
Pages: 254 pages
File Type: PDF
File Size: 115.7 MB
Other Info: Royal Society of Chemistry
   Science/Engineering Quadruplex Nucleic Acids

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Stephen Neidle, Shankar Balasubramanian. " Quadruplex Nucleic Acids "

Quadruplex Nucleic Acids (RSC Biomolecular Sciences)

By Stephen Neidle, Shankar Balasubramanian

Description:

Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered.

Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability. The biology of quadruplexes and G-rich genomic regions and G-quartets in supramolecular chemistry and nanoscience are also considered.

Surveying the current state of knowledge, and with contributions from leading experts, this is the first comprehensive review of this rapidly growing area. Quadruplex Nucleic Acids is ideal for researchers interested in areas related to chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology.

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Science/Engineering Quadruplex Nucleic Acids (RSC Biomolecular Sciences)

Science/Engineering Quadruplex Nucleic Acids (RSC Biomolecular Sciences)

Author: Publisher: Royal Society of Chemistry (2006)Binding: Hardcover, 254 pagespricer: $149.00ISBN-10: 0854043748editorialreviewsGuanine rich DNA has been known for decades to form unusual structures, although their biological relevance w ...

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