Youn PNatGPLP rar (0127729402)

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PNH and the GPI-Linked Proteins Publisher: Academic Press

Number Of Pages: 296

Publication Date: 2000-02

Sales Rank: 730540

ISBN / ASIN: 0127729402

EAN: 9780127729404

Binding: Hardcover

Manufacturer: Academic Press

Studio: Academic Press

Average Rating: 3 Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.

Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.

This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins. Key Features

* Outlines the chemical features of PNH

* Explains the mechanism of hemolysis

* Includes work on the biochemistry of glycophosphoinositol anchors

* Contains descriptions of the chemistry and biophysics of GPI-anchored proteins Buy Book at Lowest Price on Amazon

Rating:
2.5 out of 5 by Book123

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