Medical Pharmaceutical Biotechnology Second Edition (0849318734)

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More Pharmaceutical Biotechnology Second Edition

edited by Michael J. Groves

432pages | pdf | size: 14,91 Mb

Pharmaceutical Biotechnology explores the development of protein-based therapeutic substances.

Features:

& 8226; Provides a working knowledge of the preparation, stability, and formulation of protein and peptide drugs

& 8226; Examines the successful evolution of humanized monoclonal antibodies (MAbs) to treat rheumatoid arthritis and other diseases

& 8226; Considers the currently disappointing results of genetic engineering and genomics that have isolated disease-responsible genes without significant clinical effect to date

& 8226; Looks at the market and scientific reasons behind the failure of many biotechnology products to live up to their hype

& 8226; Discusses regulatory and compendial issues and concludes with a look at future challenges facing biotechnology

Contents

Proteins

Recombinant DNA Basics

Monoclonal Antibodies

Proteomics: A New Emerging Area of Biotechnology

Commonly Used Analytical Techniques for Biotechnology Products

Formulation of Proteins and Peptides

Proteins as Drug Delivery Systems

Proteins and Phospholipids

Pulmonary Drug Delivery Systems for Biomacromolecules

Polymeric Systems for Oral Proten and Peptide Delivery

Vaccines: Ancient Medicines to Modern Therapeutics

Gene Therapy: An Overview of Current Viral and Non-Viral Vectors

Regulatory and Compendial Issues

Some Challenges Relating to the Future of Biopharmaceutical Technology

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