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Medical Optimization in Drug Discovery (Methods in Pharmacology and Toxicology)
Posted on 2010-03-15
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Optimization in Drug Discovery (Methods in Pharmacology and Toxicology) Publisher: Humana Press
Number Of Pages: 436 Publication Date: 2004-09 Sales Rank: 1194865 ISBN / ASIN: 1588293327 EAN: 9781588293329 Binding: Hardcover Manufacturer: Humana Press Studio: Humana Press Book Description: A panel of researchers and experts from leading universities and major pharmaceutical companies from all over the world systematically describe cutting-edge experimental protocols for the early in vitro evaluation of new chemical entities (NCE). These readily reproducible assays measure such critical parameters as physicochemical properties, adsorption, plasma freeduan.com binding, metabolism, drug interactions, and toxicity. By uncovering early in the discovery stage the defects that can eliminate candidate drugs from preclinical and clinical development, these techniques can save millions of dollars in time and effort.
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