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Science/Engineering New Treatment Strategies for Metastatic Colorectal Cancer

Posted on 2010-03-15




Name:Science/Engineering New Treatment Strategies for Metastatic Colorectal Cancer
ASIN/ISBN:1595675775
Language:English
File size:3.3 Mb
Pages: 138 pages
Publish Date: 2008
ISBN: 1595675775
File Type: PDF
Other Info: CMPMedica; 3.3mb
   Science/Engineering New Treatment Strategies for Metastatic Colorectal Cancer

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Edward Chu, MD"New Treatment Strategies for Metastatic Colorectal Cancer"

Colorectal cancer (CRC) is a major public health problem in the United States and throughout the world. Each year, this disease affects nearly 150,000 new patients, and it is the second leading cause of mortality, accounting for almost 50,000 deaths in the United States.

Colorectal cancer (CRC) is a major public health problem in the United

States and throughout the world. Each year, this disease affects nearly

150,000 new patients, and it is the second leading cause of mortality,

accounting for almost 50,000 deaths in the United States. Worldwide,

CRC afflicts nearly 800,000 individuals and is associated with 500,000

deaths. Over the past 10 years, significant advances have been made in

the screening and early detection of CRC as well as in the different treatment

approaches, including surgery, radiation therapy, and chemotherapy,

which are now available for patients with early-stage CRC and

more advanced stages of the disease. Without question, CRC has now

become a highly preventable and curable disease through regular screenings

and early detection, and highly treatable when diagnosed at an even

more advanced stage.

In this book, we have condensed and summarized a wealth of information

on the treatment approaches for patients with advanced, metastatic

CRC and present essential information in a practical and readable

format. It is critical that a team of physicians from various specialties,

including surgery, radiation oncology, medical oncology, pathology, and

radiology, provide their special expertise in developing individual treatment

plans for patients with CRC. The first chapter focuses on the biology

of CRC and the key pathways involved in cancer formation,

whereas the last chapter provides a nice overview of the role of prognostic

and predictive biomarkers that are now being developed for this disease.

The three middle chapters are devoted to an update on the role of

cytotoxic chemotherapy, the integration of biologic agents in treatment

regimens, and the role of a combined modality approach to treat

patients with liver-limited metastatic disease. These chapters provide

timely review of the most up-to-date information presently available.

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