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The Pharmacological Basis of Therapeutics, 11th Edition

CONTENTS

I. General Principles

Chapter 1. Pharmacokinetics and Pharmacodynamics: The Dynamics of Drug Absorption, Distribution, Action, and Elimination UPDATED*

Chapter 2. Membrane Transporters and Drug Response

Chapter 3. Drug Metabolism

Chapter 4. Pharmacogenetics

Chapter 5. The Science of Drug Therapy

II. Drugs Acting at Synaptic and Neuroeffector Junctional Sites

Chapter 6. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems

Chapter 7. Muscarinic Receptor Agonists and Antagonists

Chapter 8. Anticholinesterase Agents

Chapter 9. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

Chapter 10. Adrenergic Agonists and Antagonists

Chapter 11. 5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists

III. Drugs Acting on the Central Nervous System

Chapter 12. Neurotransmission and the Central Nervous System

Chapter 13. General Anesthetics

Chapter 14. Local Anesthetics

Chapter 15. Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium

Chapter 16. Hypnotics and Sedatives

Chapter 17. Drug Therapy of Depression and Anxiety Disorders

Chapter 18. Pharmacotherapy of Psychosis and Mania

Chapter 19. Pharmacotherapy of the Epilepsies

Chapter 20. Treatment of Central Nervous System Degenerative Disorders

Chapter 21. Opioid Analgesics

Chapter 22. Ethanol

Chapter 23. Drug Addiction and Drug Abuse

IV. Autacoids: Drug Therapy of Inflammation

Chapter 24. Histamine, Bradykinin, and Their Antagonists

Chapter 25. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor UPDATED*

Chapter 26. Analgesic-Antipyretic and Antiinflammatory Agents; Pharmacotherapy of Gout UPDATED*

Chapter 27. Pharmacotherapy of Asthma

V. Drugs Affecting Renal and Cardiovascular Function

Chapter 28. Diuretics

Chapter 29. Vasopressin and Other Agents Affecting the Renal Conservation of Water

Chapter 30. Renin and Angiotensin

Chapter 31. Treatment of Myocardial Ischemia UPDATED*

Chapter 32. Therapy of Hypertension

Chapter 33. Pharmacotherapy of Congestive Heart Failure

Chapter 34. Antiarrhythmic Drugs

Chapter 35. Drug Therapy for Hypercholesterolemia and Dyslipidemia UPDATED*

VI. Drugs Affecting Gastrointestinal Function

Chapter 36. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease UPDATED*

Chapter 37. Treatment of Disorders of Bowel Motility and Water Flux; Antiemetics; Agents Used in Biliary and Pancreatic Disease

Chapter 38. Pharmacotherapy of Inflammatory Bowel Disease

VII. Chemotherapy of Parasitic Infections

Chapter 39. Chemotherapy of Protozoal Infections: Malaria

Chapter 40. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections

Chapter 41. Chemotherapy of Helminth Infections

VIII. Chemotherapy of Microbial Diseases

Chapter 42. General Principles of Antimicrobial Therapy

Chapter 43. Sulfonamides, TrimethoprimSulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections

Chapter 44. Penicillins, Cephalosporins, and Other -Lactam Antibiotics

Chapter 45. Aminoglycosides

Chapter 46. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents

Chapter 47. Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy

Chapter 48. Antimicrobial Agents: Antifungal Agents

Chapter 49. Antiviral Agents (Nonretroviral)

Chapter 50. Antiretroviral Agents and Treatment of HIV Infection

IX. Chemotherapy of Neoplastic Diseases

Chapter 51. Antineoplastic Agents

X. Immunomodulators

Chapter 52. Immunosuppressants, Tolerogens, and Immunostimulants

XI. Drugs Acting on the Blood and the Blood-Forming Organs

Chapter 53. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins

Chapter 54. Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugs UPDATED*

XII. Hormones and Hormone Antagonists

Chapter 55. Pituitary Hormones and Their Hypothalamic Releasing Hormones

Chapter 56. Thyroid and Antithyroid Drugs

Chapter 57. Estrogens and Progestins

Chapter 58. Androgens

Chapter 59. Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones

Chapter 60. Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas UPDATED*

Chapter 61. Agents Affecting Mineral Ion Homeostasis and Bone Turnover

XIII. Dermatology

Chapter 62. Dermatological Pharmacology

XIV. Ophthalmology

Chapter 63. Ocular Pharmacology

XV. Toxicology

Chapter 64. Principles of Toxicology and Treatment of Poisoning

Chapter 65. Heavy Metals and Heavy-Metal Antagonists

Appendices

Appendix I. Principles of Prescription Order Writing and Patient Compliance

Appendix II. Design and Optimization of Dosage Regimens: Pharmacokinetic Data

* UPDATED chapters feature new content found exclusively in Goodman & Gilman's Online via AccessMedicine and not available from any other print or online source.

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