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Neuroprotection in Brain Ischemia: An Update

Posted on 2010-03-16




Name:Neuroprotection in Brain Ischemia: An Update
ASIN/ISBN:380558122X
Language:English
File size:3.61 Mb
Publisher: Not Avail
ISBN: 380558122X
Publish Date: edition 2006
File Type: PDF
Pages: 123 pages
File Size: 3,61 mb
   Neuroprotection in Brain Ischemia: An Update

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Despite the significant advances that have been made over the past decade in delineating the cellular mechanisms of ischemic brain injury, researchers have not been able to translate these gains in basic research into clinically effective neuroprotective treatments. One major line of investigation has involved the theory of excitotoxicity, which is based on the observation that large concentrations of glutamate can destroy neurons. Now investigators have identified new, glutamate-independent targets for neuroprotection in brain ischemia. The findings may have important implications for the development of a new clinical paradigm for neuroprotection, according to Roger P. Simon, MD. Dr. Simon is Director of Neurobiology Research and Chair in Neurology at the Robert S. Dow Neurobiology Laboratories in Portland, Oregon.

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