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Science/Engineering Neurogenic Inflammation in Health and Disease (NeuroImmune Biology)

Posted on 2010-03-15




Name:Science/Engineering Neurogenic Inflammation in Health and Disease (NeuroImmune Biology)
ASIN/ISBN:0444532293
Language:English
File size:2.4 Mb
Publish Date: 2009-01-26
ISBN: 0444532293
Pages: 368 pages
File Type: PDF
File Size: 2,4 MB
Other Info: Elsevier Science
   Science/Engineering Neurogenic Inflammation in Health and Disease (NeuroImmune Biology)

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Gabor Jancso, "Neurogenic Inflammation in Health and Disease (NeuroImmune Biology)"

Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain.

* Neurogenic inflammation in historical perspective

* Cardiac protection by nociceptive afferents

* Molecular mechanisms of nociception

* Sensory mechanisms in migraine pathophysiology

* Vagal signalling of visceral inflammation

* Neurogenic mechanisms in arthritis

* Therapeutic implications of vanilloid-type compounds

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