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Natural Genetic Engineering and Natural Genome Editing

series: New York Academy of Sciences, Annals, Volume 1178

The recent literature on whole genome sequences provides abundant evidence for the action of natural genetic engineering in evolution. Discoveries about natural genetic engineering have coincided with rapid progress in our understanding of epigenetic control and RNA-directed chromatin formation. Special attention needs to be paid to the role of viruses and related so-called "parasitic" elements in the origin of genome formatting and natural genetic engineering capabilities especially the role of non-random genetic change operators in the production of complex evolutionary inventions. This volume, stemming from the symposium “Natural Genetic Engineering and Natural Genome Editing” (3-6 July 2008, Salzburg, Austria), contains contributions from scientists working on genome organization, genome restructuring, genome formatting and virus research in the context of evolution, development, and disease. From the Buy Book at Lowest Price on Amazon

. Including:

Introduction : A Perspective on Natural Genetic Engineering and Natural Genome Editing (p 1-5) BY Günther Witzany

Part I. Information Processing Replaces Mechanics

Revisiting the Central Dogma in the 21st Century (p 6-28) BY James A. Shapiro

Deconstructing the Dogma : A New View of the Evolution and Genetic Programming of Complex Organisms (p 29-46) BY John S. Mattick

On the Origin of Cells and Viruses : Primordial Virus World Scenario (p 47-64) BY Eugene V. Koonin

The Great Billion-year War between Ribosome- and Capsid-encoding Organisms (Cells and Viruses) as the Major Source of Evolutionary Novelties (p 65-77) BY Patrick Forterre, David Prangishvili

Learning from Bacteria about Natural Information Processing (p 78-90) BY Eshel Ben-Jacob

Part II. Viral Infection-driven Eukaryotic Evolution

The Viral Eukaryogenesis Hypothesis : A Key Role for Viruses in the Emergence of Eukaryotes from a Prokaryotic World Environment (p 91-105) BY Philip John Livingstone Bell

Cell-Cell Channels, Viruses, and Evolution : Via Infection, Parasitism, and Symbiosis toward Higher Levels of Biological Complexity (p 106-119) BY Frantiscaronek Baluscaronka

Impact of RNA Virus Infection on Plant Cell Function and Evolution (p 120-128) BY Annette Niehl, Manfred Heinlein

Hen or Egg? : Some Thoughts on Tunneling Nanotubes (p 129-136) BY Amin Rustom

Part III. Communal Evolution

Evolution of Genes and Organisms : The Tree/Web of Life in Light of Horizontal Gene Transfer (p 137-145) BY Lorraine Olendzenski, J. Peter Gogarten

The Natural Genetic Engineering of Polydnaviruses (p 146-156) BY Bruce Webb, Tonja Fisher, Tyasning Nusawardani

Friendly Viruses : The Special Relationship between Endogenous Retroviruses and Their Host (p 157-172) BY Mariana Varela, Thomas E. Spencer, Massimo Palmarini, Frederick Arnaud

Natural Genetic Engineering of Hepatitis C Virus NS5A for Immune System Counterattack (p 173-185) BY Mahmoud M. El Hefnawi, Wessam H. El Behaidy, Aliaa A. Youssif, Atek Z. Ghalwash, Lamya A. El Housseiny, Suher Zada

Part IV. Modular Interacting Agents

The Fragmented Gene (p 186-193) BY Jürgen Brosius

The Source of Self : Genetic Parasites and the Origin of Adaptive Immunity (p 194-232) BY Luis P. Villarreal

Cellular Genes Derived from Gypsy/Ty3 Retrotransposons in Mammalian Genomes (p 233-243) BY Jean-Nicolas Volff

Noncoding RNAs: Persistent Viral Agents as Modular Tools for Cellular Needs (p 244-267) BY Günther Witzany

APOBEC3 Proteins Inhibit LINE-1 Retrotransposition in the Absence of ORF1p Binding (p 268-275) BY Nika Lovscaronin, B. Matija Peterlin

Part V. Epigenetic Control

Epigenetic Regulation of Mammalian Genomes by Transposable Elements (p 276-284) BY Ahsan Huda, I. King Jordan

Are There Epigenetic Controls in Trypanosoma cruzi? (p 285-290) BY Maria Carolina Elias, Marcella Faria

Conceptual and Methodological Biases in Network Models (p 291-304) BY Ehud Lamm

No Genetics without Epigenetics? No Biology without Systems Biology? : On the Meaning of a Relational Viewpoint in a Complex Account of Living Systems (p 305-317) BY Gertrudis Van de Vijver

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