Science/Engineering Mucosal Immune Defense: Immunoglobulin A (0387722319)

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Publisher: Springer (2007)

Binding: Hardcover, 433 pages

pricer: $129.00

ISBN-10: 0387722319

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Immune responses at mucosal surfaces play a major role in host mucosal defense against microbial pathogens and in the pathogenesis of acute and chronic mucosal inflammatory diseases. This volume draws on a broad spectrum of molecular biologic, biochemical, and immunogenetic approaches in combination with human and murine in vitro cell culture and in vivo model systems to address questions in mucosal immunity. Humans produce more immunoglobulin A (IgA) than all other antibody isotypes combined, most of which is rapidly transported into the external secretions bathing mucous membranes. It has been estimated that more than 3 grams of IgA are transported daily into mucosal secretions, carrying out a wide range of antimicrobial and anti-inflammatory functions. IgA is the second most abundant class of antibody in the bloodstream, contributing to systemic as well as secretory immunity. Recent advances in human genomics, gene regulation, structural biology, cell signaling, and immunobiology have greatly enhanced our understanding of this important class of antibody. This book is designed to serve as a concise reference of the present knowledge of the biology of IgA, including structure of IgA and its interaction with Fc receptors; epithelial transport of IgA; regulation of the mucosal IgA system; biological roles of IgA, including newly discovered functions; IgA-associated diseases, and therapeutic applications for IgA. Chapters have been contributed by internationally recognized leaders in the field of IgA research, representing 8 countries on 3 continents.

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	Health Mucosal Immunology and Virology Mucosal Immunology and Virology Publisher: SpringerNumber Of Pages: 214Publication Date: 2006-08-17Sales Rank: 2490251ISBN / ASIN: 1846282012EAN: 9781846282010Binding: HardcoverManufacturer: SpringerStudio: SpringerAverag ...
	In Defense of Self: How the Immune System Really Works (2008) In Defense of Self: How the Immune System Really WorksPublisher: Oxford University Press \| Language: English \| ISBN: 0195335554 \| 288 pages \| Data: 2008 \| PDF \| 1.3 MbDescription: We live in a sea of seething microbial predators, an infini ...
	In Defense of Self: How the Immune System Really Works Publisher: Oxford University PressLanguage: EnglishISBN: 0195335554Paperback: 288 pagesData: 2008Format: PDFDescription: We live in a sea of seething microbial predators, an infinity of invisible and invasive microorganisms capable of sett ...
	Mucosal Immune Defense: Immunoglobulin A (2007) Mucosal Immune Defense: Immunoglobulin APublisher: Springer \| Language: English \| ISBN:0387722319 \| 446 pages \| Data: 2007 \| PDF \| 4 MbDescription: Immune responses at mucosal surfaces play a major role in host mucosal defense against micr ...
	Science/Engineering Use of Intravenous Immunoglobulin in Clinical Dermatology Use of Intravenous Immunoglobulin in Clinical Dermatology Publisher:Informa Healthcare \| Pages:208 \| 2002-12-19 \| ISBN:1841841366 \| PDF \| 2.5 MBIntravenous Immunoglobulins in Dermatology is the first book to bring together the latest ...
	Science/Engineering William R. Clark - In Defense of Self: How the Immune System Really Works William R. Clark - In Defense of Self: How the Immune System Really WorksOxford University Press \| 2008 \| ISBN: 0195335554 \| Pages: 288 \| PDF \| 1.10 MBWe live in a sea of seething microbial predators, an infinity of invisible and invasive m ...

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