Medical Monosaccharide Sugars: Chemical Synthesis by Chain Elongation, Degradation, and Epimerization (0125503601)

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Monosaccharide Sugars: Chemical Synthesis by Chain Elongation, Degradation, and Epimerization By Zoltan Gyorgydeak, Istvan Pelyvas, Publisher: Academic Press

Number Of Pages: 508

Publication Date: 1998-01-15

Sales Rank: 4284377

ISBN / ASIN: 0125503601

EAN: 9780125503600

Binding: Hardcover

Manufacturer: Academic Press

Studio: Academic Press

In a single volume, Monosaccharide Sugars critically summarizes the applied and potentially useful strategies for the synthesis and degradation of monosaccharides by chain-elongation, degradation, and epimerization. These methodologies permit the synthesis of rare or unnatural monosaccharides that are frequently employed as chiral building blocks in natural products synthesis, as well as for producing sugar derivatives labeled with radioactive isotopes. Representative and well-established experimental procedures are provided to illustrate the potential of the synthetic transformation.Degradation of carbohydrates also represents an invaluable tool for the structural elucidation of certain natural products, suchas glycosides, antibiotics, and polysaccharides. When describing the individual methods, unique supplementary collections of the prepared sugar derivatives are shown in tabular form. This compendium will eliminate tedious literature searches for those engaged in research and teaching on the chemistry and biochemistry of saccharides and other natural products, and also for those working on the medicinal and metabolic investigation of related substances of biological importance. Key Features

* Illustrates the practical potential of well-established experimental procedures in synthetic transformations

* Provides supplementary collections of prepared sugar derivatives in tabular form

* Summarizes in a single volume the methods of obtaining carbohydrate-derived compounds

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