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Molecular Mechanisms of Cockayne Syndrome By: Shamim I. Ahmad

Cockayne syndrome (CS) is a rare autosomal genetic disorder that was first identifi edalmost 62 years ago by Alfred Cockayne and was named after him. The earliest publication record (PubMed) available is a paper by Marie et al in 1958. Since then 815 research papers including excellent reviews have been published (PubMed, December 2008), yet we are a long way from fully understanding the exact molecular mechanisms of this disease. Ironically, like many other inborn genetic defects, CS is still incurable.

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