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Medical Mitochondrial Inhibitors and Neurodegenerative Disorders (Contemporary Neuroscience)
Posted on 2010-03-15
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Mitochondrial Inhibitors and Neurodegenerative Disorders (Contemporary Neuroscience) Publisher: Humana Press
Number Of Pages: 360 Publication Date: 1999-10-01 Sales Rank: 2013829 ISBN / ASIN: 089603805X EAN: 9780896038059 Binding: Hardcover Manufacturer: Humana Press Studio: Humana Press Average Rating: 5 Respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These read.freeduan.com distinguished researchers-many pioneers in the field-detail the symptomology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The emphasis on 3-NP and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease demonstrate that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. The book also discusses recent therapeutic modalities aimed at rescuing the central nervous system from abnormal mitochodrial functioning. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression. Review: Excellent neuroscience research book. For those interested in research on neurodegeneration, this book provides compelling evidence of the effects of mitochondrial impairment on cell death. The book covers specialty topics including animal models of neurological disorders and novel repair strategies conducted by leading scientists around the world.
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