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Science/Engineering Mechanisms and Models in Rheumatoid Arthritis By B. Henderson, J. G. Edwards, E. R. Pettipher
Posted on 2010-03-16
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More Mechanisms and Models in Rheumatoid Arthritis By B. Henderson, J. G. Edwards, E. R. Pettipher Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.
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