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Mathematical Modeling of Biosensors: An Introduction for Chemists and Mathematicians

Posted on 2010-03-16




Name:Mathematical Modeling of Biosensors: An Introduction for Chemists and Mathematicians
ASIN/ISBN:9048132428
Language:English
File size:5.5 Mb
Publisher: Springer
ISBN: 9048132428
Publish Date: edition 2009
File Type: PDF
Pages: 334 pages
File Size: 5,5 mb
   Mathematical Modeling of Biosensors: An Introduction for Chemists and Mathematicians

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This book presents biosensor development and modeling from both a chemical and a mathematical point of view. It contains unique modeling methods for catalytical (amperometric, potentiometer and optical) biosensors. It examines processes that occur in the sensors' layers and at their interface, and it provides analytical and numerical methods to solve enzymatic kinetic and diffusion equations. The action of single enzyme as well as polyenzyme biosensors is studied, and the modeling of biosensors that contain perforated membranes and multipart mass transport profiles is critically investigated. Furthermore, it is fully described how signals can be biochemically amplified, how cascades of enzymatic substrate conversion are triggered, and how signals are processed via a chemometric approach and artificial neuronal networks. The results of digital modeling are compared with both proximal analytical solutions and experimental data.

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