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Kevin Coward, Mark D. Baker – Sodium Channels, Pain, and Analgesia

Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sodium channel sub-types are potentially important drug targets in the treatment of pain. The roles of sodium channels in dental and visceral pain are also addressed. The emerging role of sodium channel Nav1.3 in neuropathic states is another important theme.

Authors from the pharmaceutical industry discuss pharmacological approaches to the drug targeting of sodium channels, and in particular Nav1.8, exclusively expressed in nociceptive neurons. The final chapter highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are being provided by tissue specific and inducible gene knock-out technology.

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	Health Sodium Channels, Pain, and Analgesia (Progress in Inflammation Research) Sodium Channels, Pain, and Analgesia (Progress in Inflammation Research) Publisher: BirkhauserNumber Of Pages: 199Publication Date: 2005-09-13Sales Rank: 2611621ISBN / ASIN: 3764370629EAN: 9783764370626Binding: HardcoverManuf ...
	Science/Engineering The Grid: Core Technologies by Maozhen Li, Mark Baker The Grid: Core Technologies by Maozhen Li, Mark BakerPublisher: John Wiley & Sons (May 27, 2005) \| ISBN-10: 0470094176 \| PDF \| 7,4 Mb \| 452 pagesFind out which technologies enable the Grid and how to employ them successfully! This invalu ...
	Science/Engineering The Grid: Core Technologies by Maozhen Li, Mark Baker The Grid: Core Technologies by Maozhen Li, Mark BakerPublisher: John Wiley & Sons (May 27, 2005) \| ISBN-10: 0470094176 \| PDF \| 4 Mb \| 452 pagesFind out which technologies enable the Grid and how to employ them successfully!This invaluab ...
	Science/Engineering Sodium Channels and Neuronal Hyperexcitability Novartis Foundation, "Sodium Channels and Neuronal Hyperexcitability"Publisher: Wiley; 1 edition \| 2001-12-15 \| 267 Pages \| ISBN: 0471485306 \| PDF \| 1.7 MBRecent progress has led to a better understanding of the molecular structure of sodiu ...
	Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management Hardcover: 541 pages Publisher: Wiley; 1 edition (August 7, 2009) Language: English ISBN-10: 047025131X ISBN-13: 978-0470251317 Peripheral Receptor Targets for AnalgesiaNovel Approaches to Pain Management Edited by Brian E ...
	Science/Engineering Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity, Volume 47 (Current Topics in Membranes) Dale J. Benos, Douglas M. Fambrough,"Amiloride-Sensitive Sodium Channels"Academic Press \| 1999-05-07 \| ISBN: 0121533476 \| PDF \| Pages:416 \| 20.5mbSodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some example ...

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	Health Sodium Channels, Pain, and Analgesia (Progress in Inflammation Research) Sodium Channels, Pain, and Analgesia (Progress in Inflammation Research) Publisher: BirkhauserNumber Of Pages: 199Publication Date: 2005-09-13Sales Rank: 2611621ISBN / ASIN: 3764370629EAN: 9783764370626Binding: HardcoverManuf ...
	Science/Engineering The Grid: Core Technologies by Maozhen Li, Mark Baker The Grid: Core Technologies by Maozhen Li, Mark BakerPublisher: John Wiley & Sons (May 27, 2005) \| ISBN-10: 0470094176 \| PDF \| 7,4 Mb \| 452 pagesFind out which technologies enable the Grid and how to employ them successfully! This invalu ...
	Science/Engineering The Grid: Core Technologies by Maozhen Li, Mark Baker The Grid: Core Technologies by Maozhen Li, Mark BakerPublisher: John Wiley & Sons (May 27, 2005) \| ISBN-10: 0470094176 \| PDF \| 4 Mb \| 452 pagesFind out which technologies enable the Grid and how to employ them successfully!This invaluab ...
	Science/Engineering Sodium Channels and Neuronal Hyperexcitability Novartis Foundation, "Sodium Channels and Neuronal Hyperexcitability"Publisher: Wiley; 1 edition \| 2001-12-15 \| 267 Pages \| ISBN: 0471485306 \| PDF \| 1.7 MBRecent progress has led to a better understanding of the molecular structure of sodiu ...
	Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management Hardcover: 541 pages Publisher: Wiley; 1 edition (August 7, 2009) Language: English ISBN-10: 047025131X ISBN-13: 978-0470251317 Peripheral Receptor Targets for AnalgesiaNovel Approaches to Pain Management Edited by Brian E ...
	Science/Engineering Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity, Volume 47 (Current Topics in Membranes) Dale J. Benos, Douglas M. Fambrough,"Amiloride-Sensitive Sodium Channels"Academic Press \| 1999-05-07 \| ISBN: 0121533476 \| PDF \| Pages:416 \| 20.5mbSodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some example ...

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