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Isaac S. Kohane, Alvin Kho, Atul J. Butte, "Microarrays for an Integrative Genomics"

Posted on 2010-04-14




Name:Isaac S. Kohane, Alvin Kho, Atul J. Butte, "Microarrays for an Integrative Genomics"
ASIN/ISBN:0262612100
File size:5 Mb
ISBN: 0262612100
Publish Date: 2005 Year
File Size: 5 Mb
Pages: 326 Pages
Other Info: The MIT Press; DjVu
   Isaac S. Kohane, Alvin Kho, Atul J. Butte, "Microarrays for an Integrative Genomics"

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& 8220;Functional genomics — the deconstruction of the genome to determine the biological function of genes and gene interactions — is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.

This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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