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Introduction to Computational Biology: An Evolutionary Approach (repost)

Posted on 2010-03-16




Name:Introduction to Computational Biology: An Evolutionary Approach (repost)
ASIN/ISBN:3764367008
Language:English
File size:2.2 Mb
Publish Date: 2006
ISBN: 3764367008
Pages: 328 pages
File Type: PDF
File Size: 2,2 MB
Other Info: Birkhauser
   Introduction to Computational Biology: An Evolutionary Approach (repost)

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Bernhard Haubold, Thomas Wiehe, "Introduction to Computational Biology: An Evolutionary Approach"

Analysis of molecular sequence data is the main subject of this introduction to computational biology. There are two closely connected aspects to biological sequences: (i) their relative position in the space of all other sequences, and (ii) their movement through this sequence space in evolutionary time. Accordingly, the first part of the book deals with classical methods of sequence analysis: pairwise alignment, exact string matching, multiple alignment, and hidden Markov models. In the second part evolutionary time takes left stage and phylogenetic reconstruction, the analysis of sequence variation, and the dynamics of genes in populations are explained in detail. In addition, the book contains a computer program with a graphical user interface that allows the reader to experiment with a number of key concepts developed by the authors. This textbook is intended for students enrolled in courses in computational biology or bioinformatics as well as for molecular biologists, mathematicians, and computer scientists.

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