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Medical Innate and Adaptive Immunity in the Tumor Microenvironment

Posted on 2010-03-16




Name:Medical Innate and Adaptive Immunity in the Tumor Microenvironment
ASIN/ISBN:1402067496
Author:Eitan Yefenof
Publisher:Springer
Publish Date:Jan 2008
Language:English
Pages:216
File size:2.5 Mb
   Medical Innate and Adaptive Immunity in the Tumor Microenvironment

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  • Author: Eitan Yefenof
  • Publisher: Springer
  • Publish Date: Jan 2008
  • ISBN: 1402067496
  • Pages: 216
Cancer cells are continuously interacting with the immune system of the host. These interactions can be regarded as a double edged sword. On the one hand, innate and adaptive immune responses act to protect the host by attempting rejection of the tumor. On the other hand, inflammatory cells and proteins stimulate multiplication and dissemination of cancer cells, thereby accelerating the progression of the disease. Traditionally, the interplay between cancer cells and host immunity has been studied systemically, with no particular attention to the site at which a given tumor develops. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. Accordingly, microenvironmental immunity that operates inside and around a tumor plays a crucial role in cancer development and progression. The aim of the present volume is to compile reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease. These reviews have been solicited from experts in the field who published original research studies focusing on these issues. Buy Book at Lowest Price on Amazon

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