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Hypocretins: Integrators of Physiological Signals
Posted on 2010-04-28
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Publisher: Springer (2005) Binding: Hardcover, 439 pages pricer: $139.00 ISBN-10: 038725000X editorialreviews The hypocretins (orexins) are a newly identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides, located primarily in the hypothalmus, in the regulation of behavioral state. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy). checked
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