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Handbook of Single-Molecule Biophysics

Posted on 2010-03-16




Name:Handbook of Single-Molecule Biophysics
ASIN/ISBN:0387764968
Language:English
File size:48.5 Mb
Language: English
Publish Date: 18 Aug 2009
ISBN: 0387764968
Pages: 626 pages
File Type: PDF
File Size: 48,5 MB
Other Info: Springer-Verlag
   Handbook of Single-Molecule Biophysics

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During the last decade, a number of novel biophysical methods have been developed that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at the fundamental level of sensitivity, that of a single molecule, has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them. Editorial Advisory Board: Daniel M?ller, Cheng Zhu, Claus Seidel, Xiaowei Zhuang, Thomas Schmidt, Nynke Dekker.

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