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Science/Engineering Handbook of Drug Metabolism

Posted on 2010-03-15




Name:Science/Engineering Handbook of Drug Metabolism
ASIN/ISBN:0824702298
Language:English
File size:31.9 Mb
Publisher: Informa HealthCare
Pages: 612
Publish Date: 1999-03-29
ISBN: 0824702298
File Type: PDF
File Size: 31.9 MB
   Science/Engineering Handbook of Drug Metabolism

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Handbook of Drug Metabolism

Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.

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