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Medical Genomic Disorders: The Genomic Basis of Disease
Posted on 2010-03-15
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Genomic Disorders: The Genomic Basis of Disease Publisher: Humana Press
Number Of Pages: 448 Publication Date: 2006-04-15 Sales Rank: 1958877 ISBN / ASIN: 1588295591 EAN: 9781588295590 Binding: Hardcover Manufacturer: Humana Press Studio: Humana Press A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
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